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doi:10.1007/s00204-021-03104-1

Interestingly, Fab 3F52 blocked the BMS21-induced response with potency in the low nanomolar range, similar to the inhibition of native GLP-1

MG causes apoptosis in a dose-dependent manner in RINm5F cells and other rat pancreatic beta cells 4

Weight regain after semaglutide withdrawal in the STEP 1 extension further suggests that treatment-related changes in appetite and weight regulation may not persist uniformly after discontinuation (95)